Cosentyx (secukinumab) is a biologic drug that is used to treat various autoimmune diseases such as psoriasis, psoriatic arthritis, and ankylosing spondylitis. Adjusting the dosage of Cosentyx may have both benefits and risks, and it is important to understand these risks before making any changes to the treatment plan.

According to Drug Patent Watch [1], the recommended dosage of Cosentyx is based on the patient's body weight and the specific condition being treated. The initial dose is typically higher, followed by a maintenance dose. The dosage may be adjusted based on the patient's response to treatment, but any changes should be made under the guidance of a healthcare professional.

Medscape [2] notes that adjusting the dosage of Cosentyx may increase the risk of adverse effects, such as infections, allergic reactions, and injection site reactions. These risks may be higher if the dosage is increased too quickly or if the patient has a history of these types of reactions.

A recent study published in the Journal of Dermatological Treatment [3] found that adjusting the dosage of Cosentyx may also impact its effectiveness in treating psoriasis. The study suggests that patients who received a higher dosage of Cosentyx had a better response to treatment, but also experienced more adverse effects.

In summary, adjusting the dosage of Cosentyx may have both benefits and risks. Any changes to the treatment plan should be made under the guidance of a healthcare professional, taking into account the patient's individual response to treatment and the potential risks of adverse effects. Patients should also be aware that adjusting the dosage may impact the effectiveness of the drug in treating their condition.

Sources:
[1] https://www.drugpatentwatch.com/p/biologics/tradename/COSENTYX
[2] https://reference.medscape.com/drug/cosentyx-secukinumab-999964
[3] https://pubmed.ncbi.nlm.nih.gov/33891380/