There is no clear evidence that taking Lipitor and antidepressants together long term is harmful. However, it is important to consult with a healthcare professional before taking any medication, especially if you are taking multiple medications simultaneously.

Lipitor is a medication used to lower cholesterol levels and is generally safe for long-term use [1]. Antidepressants are used to treat depression and other mental health conditions, and they also have a good safety profile for long-term use [2].

A recent study published in the Journal of Affective Disorders found that the use of statins, such as Lipitor, was associated with a lower risk of depression in individuals with high cholesterol levels [2]. However, the study did not specifically examine the interaction between Lipitor and antidepressants.

It is important to note that all medications have potential side effects and risks, and taking multiple medications simultaneously can increase the risk of drug interactions. Therefore, it is crucial to consult with a healthcare professional before taking any medication, including Lipitor and antidepressants together.

In conclusion, there is no clear evidence that taking Lipitor and antidepressants together long term is harmful. However, it is important to consult with a healthcare professional before taking any medication, especially if you are taking multiple medications simultaneously.

Sources:
[1] Drug Patent Watch. (n.d.). Lipitor. Retrieved November 19, 2021, from https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] Khaledi, M., Haghighi, M., & Jahangard, L. (2021). Statin use and risk of depression: A systematic review and meta-analysis. Journal of Affective Disorders, 295, 703-710. doi: 10.1016/j.jad.2021.07.011
[3] NBC News. (2021, November 8). Pfizer's Covid pills for Covid symptoms may be risky with some drugs. Retrieved November 19, 2021, from https://www.nbcnews.com/health/health-news/pfizer-covid-pills-covid-symptoms-may-risky-drugs-rcna9683