Lipitor is a medication used to lower cholesterol levels in the body. It belongs to a class of drugs called statins, which work by blocking an enzyme in the liver that produces cholesterol. While taking Lipitor, it is important to avoid certain proteins that may interact with the medication and increase the risk of side effects.
According to the drug label provided by Pfizer [3], grapefruit and grapefruit juice should be avoided while taking Lipitor. This is because grapefruit contains compounds that can interfere with the metabolism of the medication, leading to higher levels of the drug in the bloodstream and an increased risk of side effects.
In addition, the drug label recommends avoiding consumption of large amounts of alcohol while taking Lipitor, as this can increase the risk of liver damage. However, moderate alcohol consumption (up to one drink per day for women and up to two drinks per day for men) is generally considered safe while taking Lipitor [3].
The National Center for Biotechnology Information [2] notes that while there are no specific dietary restrictions associated with taking Lipitor, it is important to maintain a healthy diet and exercise regularly in order to achieve the best results from the medication. This may include reducing intake of saturated and trans fats, increasing consumption of fruits and vegetables, and incorporating regular physical activity into one's routine.
In summary, while taking Lipitor, it is important to avoid consuming grapefruit or grapefruit juice, and to limit alcohol consumption to moderate levels. Maintaining a healthy diet and exercise routine can also help to optimize the benefits of the medication.
Sources:
[2] National Center for Biotechnology Information. Statins. In: LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK430779/
[3] Pfizer. Lipitor (atorvastatin calcium) tablets [prescribing information]. New York, NY: Pfizer Inc.; 2020. Available from: https://labeling.pfizer.com/showlabeling.aspx?id=587