Lipitor is a prescription drug used to lower cholesterol levels in the blood. The drug is typically taken once daily, with or without food, at any time of the day [1]. As for probiotics, there is no specific recommendation for how often they should be taken in conjunction with Lipitor. However, it is important to note that certain probiotics may interact with Lipitor and other statin drugs. According to ConsumerLab, the probiotic Saccharomyces boulardii should be avoided when taking statins, as it may increase the risk of muscle damage [3]. It is always recommended to consult with a healthcare professional before starting any new supplement or medication regimen, including probiotics and Lipitor.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[3] https://www.consumerlab.com/answers/which-drugs-should-be-avoided-when-taking-statins/statin-supplement-interactions/
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904929/