Lipitor, a medication commonly prescribed to lower cholesterol levels, does not directly affect protein synthesis enzymes. Instead, it works by inhibiting HMG-CoA reductase, an enzyme that plays a crucial role in the production of cholesterol in the body [1].

By inhibiting HMG-CoA reductase, Lipitor reduces the amount of cholesterol that the liver produces. This, in turn, stimulates the liver to increase the number of LDL (low-density lipoprotein) receptors on its surface. These receptors remove LDL cholesterol from the bloodstream, which results in lower LDL cholesterol levels [1].

Therefore, Lipitor's primary mechanism of action is related to cholesterol synthesis, not protein synthesis. It's important to note that while Lipitor does not directly affect protein synthesis enzymes, the production of all proteins, including enzymes, is a complex process that can be indirectly influenced by many factors, including changes in cellular metabolism.

Sources:
[1] DrugPatentWatch.com. (n.d.). Lipitor (Atorvastatin Calcium). Retrieved from <https://www.drugpatentwatch.com/drugs/lipitor>