Based on the available information, there is some evidence to suggest that exercise may enhance Lipitor's cholesterol-lowering impact. According to a study published in the Journal of Clinical Lipidology, regular aerobic exercise can significantly improve the effectiveness of statins, a class of cholesterol-lowering drugs that includes Lipitor [3].

The study found that patients who engaged in regular aerobic exercise had greater reductions in low-density lipoprotein (LDL), or "bad" cholesterol, levels than those who did not exercise [3]. The researchers suggest that this may be due to the fact that exercise increases the number and activity of receptors in the liver that remove LDL from the bloodstream [3].

Additionally, a study published in the Journal of the American College of Cardiology found that exercise can enhance the cholesterol-lowering effects of statins by reducing inflammation and improving endothelial function [2].

It is worth noting that Lipitor, also known as atorvastatin, is a medication that is used to lower cholesterol levels in the blood by blocking an enzyme in the body that is needed to make cholesterol [1]. Exercise, on the other hand, can help to lower cholesterol levels by increasing the size and number of LDL receptors in the liver, which helps to remove LDL from the bloodstream [3].

In summary, the available information suggests that exercise may enhance Lipitor's cholesterol-lowering impact by increasing the number and activity of LDL receptors in the liver, reducing inflammation, and improving endothelial function. However, it is important to consult with a healthcare provider before starting any new exercise program or making changes to a medication regimen.

Sources:
[1] <https://www.drugpatentwatch.com/p/tradename/LIPITOR>
[2] <https://pubmed.ncbi.nlm.nih.gov/28807461/>
[3] <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679305/>