Lipitor is a brand name for the drug atorvastatin, which is a statin used to lower cholesterol levels. Grapefruit juice is known to interact with some medications, including statins like Lipitor. According to Health Harvard [2], grapefruit juice can increase the absorption of Lipitor, leading to higher levels of the drug in the bloodstream. This can increase the risk of side effects, including muscle pain and liver damage. Therefore, it is recommended to avoid consuming grapefruit juice while taking Lipitor. The interaction between grapefruit juice and Lipitor occurs because grapefruit juice contains compounds that inhibit the enzymes responsible for breaking down Lipitor in the liver. As a result, the drug stays in the body longer, leading to higher levels in the bloodstream [2]. It is important to note that the interaction between grapefruit juice and Lipitor can occur even if the juice is consumed hours before or after taking the medication [3]. Patients taking Lipitor should consult their healthcare provider regarding any potential interactions with other medications or supplements [2].

Sources:
[2] Harvard Health Publishing. Grapefruit juice and statins. Retrieved from https://www.health.harvard.edu/heart-health/grapefruit-juice-and-statins
[3] Ro. Lipitor and Grapefruit: What You Need to Know. Retrieved from https://ro.co/health-guide/lipitor-and-grapefruit/
[1] Drug Patent Watch. Lipitor. Retrieved from https://www.drugpatentwatch.com/p/tradename/LIPITOR