Yes, alcohol use can potentially contribute to the development of antibiotic-resistant bacteria. This is because alcohol consumption can disrupt the normal balance of bacteria in the gut, allowing antibiotic-resistant bacteria to overgrow [1].

Moreover, alcohol has been shown to reduce the effectiveness of certain antibiotics, such as fluoroquinolones and beta-lactams, by inhibiting the immune system's ability to fight off infections [2]. This can create an environment in which antibiotic-resistant bacteria are more likely to thrive.

It is important to note that the relationship between alcohol use and antibiotic resistance is complex and not yet fully understood. Further research is needed to fully understand the mechanisms by which alcohol use may contribute to the development of antibiotic-resistant bacteria.

In summary, alcohol use can potentially contribute to the development of antibiotic-resistant bacteria by disrupting the normal balance of bacteria in the gut and reducing the effectiveness of certain antibiotics.

Sources:

1. <https://www.drugpatentwatch.com/antibiotic-resistance-news/>
2. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798825/>