Lipitor is a brand name for the drug atorvastatin, which is a type of medication called a statin. Statins are commonly used to lower cholesterol levels in the blood and reduce the risk of heart disease and stroke. Grapefruit and its juice contain compounds that can interfere with the way the liver metabolizes certain medications, including some statins like Lipitor [2]. When grapefruit is consumed with Lipitor, it can increase the amount of the drug in the bloodstream, leading to a higher risk of side effects [3].

According to GoodRx [2], grapefruit and Lipitor should not be taken together. The website explains that grapefruit juice can increase the levels of Lipitor in the blood, which can lead to an increased risk of side effects such as muscle pain, liver damage, and kidney failure. Healthline [3] adds that grapefruit can also interfere with other medications that are metabolized by the liver, including some antibiotics, anti-anxiety drugs, and blood pressure medications.

The Drug Patent Watch [1] provides information on the potential side effects of Lipitor, which include muscle pain, weakness, and tenderness. The website explains that these side effects can be serious and may require medical attention. It is important to note that while grapefruit can increase the risk of these side effects, they can also occur without the consumption of grapefruit.

In conclusion, the sources suggest that grapefruit and Lipitor should not be taken together, as grapefruit can increase the levels of Lipitor in the blood and lead to an increased risk of side effects. It is important to talk to a healthcare provider before consuming grapefruit or making any changes to medication regimens [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.goodrx.com/classes/statins/why-cant-i-have-grapefruit-with-my-statin
[3] https://www.healthline.com/health/high-cholesterol/grapefruit-and-statins