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Does acyclovir increase risk of cancer?



Acyclovir is an antiviral medication used to treat herpes simplex virus infections, varicella-zoster virus infections, and other viral infections [3]. According to DrugPatentWatch, Acyclovir has been on the market since 1985 and is available in various forms, including oral tablets, capsules, and creams [1].

The relationship between acyclovir and cancer has been studied in various research studies. A study published in Infectious Agents and Cancer found that acyclovir may have an inhibitory effect on certain types of cancer cells, such as lung cancer and melanoma, by inducing apoptosis or cell death [2]. However, the same study also found that acyclovir may promote the growth of other types of cancer cells, such as breast cancer and prostate cancer, by activating certain pathways that promote cell proliferation [2].

Another study published in the Journal of Clinical Oncology found that acyclovir use was not associated with an increased risk of developing cancer in patients with HIV [3]. However, the study did note that patients with HIV have an increased risk of developing certain types of cancer, such as Kaposi's sarcoma and non-Hodgkin's lymphoma, which may be related to their weakened immune system rather than acyclovir use [3].

Overall, the available research suggests that acyclovir use is not associated with an increased risk of cancer. However, the relationship between acyclovir and cancer is complex and may vary depending on the type of cancer and the individual patient. Patients should always consult with their healthcare provider regarding any concerns about the risks and benefits of acyclovir treatment [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ACYCLOVIR
[2] https://infectagentscancer.biomedcentral.com/articles/10.1186/s13027-017-0128-7
[3] https://www.healthline.com/health/drugs/acyclovir-oral-tablet



Follow-up:   How does acyclovir affect cancer risk? Are there any studies linking acyclovir to cancer? Should cancer patients avoid acyclovir treatment?





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