Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the body. Like any other medication, there may be adverse effects of adjusting the dosage of Lipitor.

According to DrugPatentWatch [1], common side effects of Lipitor include headache, nausea, diarrhea, and muscle pain. However, adjusting the dosage of Lipitor can lead to more severe side effects such as liver damage, muscle damage, and kidney failure.

Medscape [2] notes that the risk of muscle damage increases with higher doses of Lipitor, especially in older adults and those with kidney or liver problems. Additionally, adjusting the dosage of Lipitor may increase the risk of drug interactions with other medications, such as blood thinners or antibiotics.

The National Center for Biotechnology Information [3] states that adjusting the dosage of Lipitor may also lead to an increased risk of developing diabetes, particularly in women. However, this risk is generally considered to be small and outweighed by the benefits of reducing cholesterol levels in the body.

In conclusion, adjusting the dosage of Lipitor can have adverse effects such as liver damage, muscle damage, kidney failure, drug interactions, and an increased risk of developing diabetes. It is important to consult with a healthcare provider before adjusting the dosage of Lipitor to minimize the risk of these adverse effects.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://reference.medscape.com/drug/lipitor-atorvaliq-atorvastatin-342446
[3] https://www.ncbi.nlm.nih.gov/books/NBK430779/