Advil and aspirin are both nonsteroidal anti-inflammatory drugs (NSAIDs) that are commonly used to relieve pain, fever, and inflammation. However, taking these two medications together may increase the risk of adverse reactions.
According to Drug Patent Watch [1], Advil contains ibuprofen as its active ingredient, while aspirin contains acetylsalicylic acid. Both medications work by blocking the production of prostaglandins, which are chemicals that cause pain, fever, and inflammation. However, aspirin also inhibits the production of thromboxane, which is a chemical that helps blood clot. This is why aspirin is often used to prevent heart attacks and strokes.
Medical News Today [2] reports that taking Advil and aspirin together may increase the risk of gastrointestinal bleeding, ulcers, and kidney damage. This is because both medications can irritate the lining of the stomach and intestines, and reduce blood flow to the kidneys. The risk of these adverse reactions is higher in people who are older, have a history of gastrointestinal problems, or take high doses of these medications.
Mayo Clinic [3] warns that some people may be allergic to aspirin, and may experience symptoms such as hives, itching, swelling, wheezing, and anaphylaxis. Aspirin allergy is more common in people with asthma, nasal polyps, and chronic urticaria. People who are allergic to aspirin should avoid taking Advil or any other NSAIDs.
In conclusion, taking Advil and aspirin together may increase the risk of adverse reactions, especially in people who are older, have a history of gastrointestinal problems, or take high doses of these medications. People who are allergic to aspirin should avoid taking Advil or any other NSAIDs. If you have any concerns about taking these medications, you should talk to your doctor or pharmacist.
Sources:
1. https://www.drugpatentwatch.com/p/tradename/ADVIL
2. https://www.medicalnewstoday.com/articles/322793
3. https://www.mayoclinic.org/diseases-conditions/drug-allergy/expert-answers/aspirin-allergy/faq-20058225