Lipitor, also known as atorvastatin, is a medication commonly prescribed to lower cholesterol levels and reduce the risk of heart disease. It belongs to a class of drugs called statins. When considering whether Lipitor can affect painkiller effectiveness, it is important to examine the information provided by the sources you provided.

The first source, Drug Patent Watch, provides information about the drug Lipitor but does not specifically mention any interactions with painkillers. It primarily focuses on the patent status of the drug and its generic versions.

The second source, the NHS website, provides a list of potential side effects of atorvastatin. While it does not specifically mention painkillers, it does note that atorvastatin can interact with other medications, including some antibiotics and antifungal medications. This suggests that atorvastatin may have the potential to interact with certain drugs, although painkillers are not specifically mentioned.

The third source, the Mayo Clinic, provides comprehensive information about atorvastatin, including its potential side effects. It does not mention any specific interactions between atorvastatin and painkillers. However, it does note that atorvastatin can interact with other medications, such as certain anticoagulants and immunosuppressants. This suggests that there is a possibility of drug interactions with atorvastatin, although painkillers are not specifically mentioned.

Based on the information provided by the sources, it is unclear whether Lipitor specifically affects the effectiveness of painkillers. While the sources mention potential interactions with other medications, painkillers are not specifically addressed. It is always important to consult with a healthcare professional or pharmacist to discuss any potential interactions between medications.

In conclusion, the sources you provided do not specifically mention whether Lipitor affects the effectiveness of painkillers. It is always advisable to consult with a healthcare professional or pharmacist for personalized advice regarding medication interactions.

Sources:
[1] Drug Patent Watch: https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] NHS: https://www.nhs.uk/medicines/atorvastatin/side-effects-of-atorvastatin/
[3] Mayo Clinic: https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20067003?p=1