Lipitor is a brand name for the drug atorvastatin, which is used to treat high cholesterol levels in the blood. According to the FDA-approved label for Lipitor [3], the recommended starting dose for most adults is 10-20 mg per day, which can be increased up to 80 mg per day if necessary. However, the appropriate dosage of Lipitor for increasing HDL cholesterol levels may vary depending on individual factors such as age, sex, and overall health.

A study published in the Journal of Lipid Research [2] found that atorvastatin treatment significantly increased HDL cholesterol levels in both men and women with high cholesterol levels. The study also found that higher doses of atorvastatin were associated with greater increases in HDL cholesterol levels. However, the study did not establish a specific safe dosage of atorvastatin for increasing HDL cholesterol levels.

Another source, Drug Patent Watch [1], provides information on the various patents and exclusivities for Lipitor. While this source does not provide information on safe dosages for HDL cholesterol specifically, it may be useful for understanding the regulatory landscape surrounding the drug.

In conclusion, while the FDA-approved label for Lipitor provides general dosage guidelines, there is no specific safe dosage of Lipitor for increasing HDL cholesterol levels. The appropriate dosage may vary depending on individual factors and should be determined by a healthcare professional. Further research may be needed to establish safe dosages for this specific use of Lipitor.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310693/
[3] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020702s057lbl.pdf