Lipitor, also known as Atorvastatin, is a medication used to lower cholesterol levels and reduce the risk of heart disease [1]. It belongs to a class of drugs called statins, which work by blocking an enzyme in the liver that produces cholesterol [3].

Regarding its interaction with painkillers, the NHS website states that taking Lipitor with non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or aspirin may increase the risk of side effects such as stomach ulcers or bleeding [2]. Therefore, it is recommended to avoid taking these painkillers unless advised by a doctor.

However, the Drug Patent Watch website does not list any specific interactions between Lipitor and painkillers [1]. Additionally, a study published in the Journal of Clinical Pharmacology found that there were no significant interactions between Lipitor and the painkiller acetaminophen (also known as paracetamol) [3].

In summary, while Lipitor may interact with certain painkillers such as NSAIDs, there is no evidence to suggest that it affects all painkillers. It is always important to consult with a doctor or pharmacist before taking any new medications, including painkillers, while on Lipitor [2].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.nhs.uk/medicines/atorvastatin/taking-atorvastatin-with-other-medicines-and-herbal-supplements/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334287/