Lipitor is a brand name for the drug atorvastatin, which is a medication used to lower cholesterol levels in the blood. Atorvastatin works by blocking an enzyme that produces cholesterol in the liver. [1]

According to the sources provided, there is no evidence to suggest that atorvastatin interacts with low-fat substitutes. However, it is important to note that atorvastatin can interact with other medications, so it is important to consult with a healthcare provider before taking any new medication or supplement. [2][3]

In terms of alternatives to atorvastatin, there are several other medications available that can lower cholesterol levels. These include statins such as simvastatin and rosuvastatin, as well as non-statin medications such as ezetimibe and bile acid sequestrants. [2][3]

It is important to remember that lifestyle changes such as a healthy diet and regular exercise can also help to lower cholesterol levels and improve overall health. [2][3]

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.singlecare.com/blog/atorvastatin-alternatives/
[3] https://www.goodrx.com/conditions/high-cholesterol/statins-alternatives-medications-for-lowering-high-cholesterol