Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood [1]. According to a study published in the Journal of Clinical Psychopharmacology, there is no significant association between the use of atorvastatin and depression [2]. However, the study also found that individuals with a history of depression may be more likely to experience depressive symptoms while taking atorvastatin.

Another study published in the journal Brain and Behavior found that simvastatin, a medication similar to atorvastatin, can change the way people experience certain emotions. The study found that simvastatin reduced the ability to experience pleasure and increased the risk of developing depression and anxiety symptoms [3].

It is important to note that these studies focus on simvastatin and not atorvastatin. While atorvastatin and simvastatin are similar medications, they have different chemical structures and may have different effects on individuals. Additionally, individual reactions to medications can vary, and it is always important to speak with a healthcare provider about any concerns or potential side effects of medication use.

In conclusion, while there is no significant association between atorvastatin use and depression, individuals with a history of depression may be more likely to experience depressive symptoms while taking atorvastatin. It is also important to note that simvastatin, a medication similar to atorvastatin, has been shown to change the way people experience certain emotions and increase the risk of developing depression and anxiety symptoms [2][3]. As with any medication, it is important to speak with a healthcare provider about any concerns or potential side effects of use.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005588/
[3] https://www.psych.ox.ac.uk/news/new-study-shows-simvastatin-can-change-the-way-people-experience-certain-emotions