Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. It belongs to a class of drugs known as statins. According to the FDA, the maximum recommended dose of Lipitor is 80 mg/day, and exceeding this dose may increase the risk of developing serious side effects [3].

One of the most common side effects of Lipitor is muscle pain and weakness. In rare cases, this can progress to a serious condition called rhabdomyolysis, which can cause kidney damage or failure [2]. The risk of rhabdomyolysis increases with higher doses of Lipitor, especially when taken in combination with certain other medications, such as fibrates or niacin [3].

Exceeding the safe Lipitor dosage may also increase the risk of liver damage, which can lead to liver failure in rare cases. The FDA recommends monitoring liver function tests before starting Lipitor and periodically thereafter, especially in patients who consume alcohol regularly or have a history of liver disease [3].

Additionally, taking high doses of Lipitor may increase the risk of developing type 2 diabetes, especially in patients with pre-existing risk factors such as obesity or metabolic syndrome [1]. This risk appears to be dose-dependent, with higher doses of Lipitor increasing the risk more than lower doses [2].

In conclusion, exceeding the safe Lipitor dosage may increase the risk of serious side effects such as muscle pain and weakness, rhabdomyolysis, liver damage, and type 2 diabetes. Patients should always follow their doctor's instructions regarding medication dosages and report any concerning symptoms immediately [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://reference.medscape.com/drug/lipitor-atorvaliq-atorvastatin-342446
[3] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020702s056lbl.pdf