Based on the information provided, I was unable to find specific data regarding dosage adjustments for the antibiotic Tigecycline in patients with liver issues. However, I did gather some general information about Tigecycline and its usage.

Tigecycline is an antibiotic used to treat various bacterial infections, such as complicated skin and skin structure infections, complicated intra-abdominal infections, and community-acquired bacterial pneumonia [1]. It is a tetracycline derivative, and its mechanism of action involves inhibiting bacterial protein synthesis [1].

When it comes to liver function, Tigecycline is primarily metabolized in the liver, and its metabolites are excreted in both feces and urine [1]. However, no specific dosage adjustments are mentioned in the FDA-approved label for Tigecycline regarding liver dysfunction [1]. Nonetheless, it is essential to use caution while administering Tigecycline to patients with hepatic impairment, as they might be at an increased risk of adverse reactions [1].

It is always recommended to consult the prescribing information or seek advice from a healthcare professional for the most accurate and up-to-date information regarding drug dosages, especially in patients with liver issues.

Sources:
[1] DrugPatentWatch.com - Tigecycline (Tygacil) - FDA Label - https://drugpatentwatch.com/drugs/tygacil/fda-label