Advil and aspirin are both nonsteroidal anti-inflammatory drugs (NSAIDs) that are commonly used to relieve pain and reduce inflammation. While these drugs can be effective when used separately, taking them together can increase the risk of side effects and complications.

One potential side effect of taking Advil and aspirin together is gastrointestinal bleeding. Both drugs can irritate the lining of the stomach and increase the risk of ulcers and bleeding [2]. This risk is especially high for people who are over 60 years old, have a history of ulcers or gastrointestinal bleeding, or take other medications that increase the risk of bleeding [3].

Another potential side effect of taking Advil and aspirin together is kidney damage. Both drugs can reduce blood flow to the kidneys and impair their function, especially in people who already have kidney problems [2]. This can lead to fluid retention, high blood pressure, and other complications.

In addition to these side effects, taking Advil and aspirin together can also increase the risk of other complications, such as heart attack, stroke, and allergic reactions [1]. These risks are especially high for people who have a history of heart disease, high blood pressure, or other medical conditions.

If you are considering taking Advil and aspirin together, it is important to talk to your doctor first. They can help you weigh the benefits and risks of these drugs and recommend alternative treatments if necessary.

Sources:

[1] https://www.healthline.com/health/pain-relief/aspirin-ibuprofen
[2] https://www.medicalnewstoday.com/articles/322793
[3] https://www.drugpatentwatch.com/p/tradename/ADVIL