Ezetimibe is a medication used to lower cholesterol levels in the blood by reducing the absorption of cholesterol from the small intestine [3]. The drug works by inhibiting the absorption of cholesterol in the small intestine by blocking the action of a protein called NPC1L1 [2]. The drug patent watch website states that ezetimibe is used in combination with other cholesterol-lowering medications, such as statins, to further reduce cholesterol levels in the blood [1].
However, there is no evidence to suggest that ezetimibe reduces fat absorption beyond its cholesterol-lowering effects. The medication has been shown to reduce the absorption of dietary cholesterol by approximately 54% but has no significant effect on the absorption of triglycerides or other fats [2].
In conclusion, ezetimibe is an effective medication for reducing cholesterol levels in the blood, but it does not reduce fat absorption beyond its cholesterol-lowering effects. It is typically used in combination with other cholesterol-lowering medications to achieve optimal results.
Sources:
[1] Drug Patent Watch. (n.d.). Ezetimibe. Retrieved from https://www.drugpatentwatch.com/p/tradename/EZETIMIBE
[2] Altmann, S. W. (2010). Ezetimibe: A novel cholesterol-lowering therapy. Proceedings (Baylor University. Medical Center), 23(2), 173–177. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858190/
[3] MedlinePlus. (2021, April 15). Ezetimibe. Retrieved from https://medlineplus.gov/druginfo/meds/a603015.html