Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels and reduce the risk of heart disease and stroke. While there is no direct evidence that Lipitor affects flexibility, there are some potential side effects that could indirectly impact flexibility.

According to the drug patent information [1], the most common side effects of Lipitor include muscle pain, weakness, and inflammation. These side effects could potentially impact flexibility, as they may cause discomfort or pain when moving certain muscles or joints. However, it's important to note that not everyone who takes Lipitor will experience these side effects.

A study published in the National Center for Biotechnology Information [2] found that while statins like Lipitor are generally safe and effective, they can sometimes cause muscle-related side effects. The study found that muscle pain and weakness were the most commonly reported side effects of statin use, and that these side effects could potentially impact physical performance.

Vascular disease, which is a condition that affects the blood vessels and can lead to reduced blood flow to the muscles, can also impact flexibility [3]. This is because reduced blood flow can cause the muscles to become stiff and less flexible.

Overall, while there is no direct evidence that Lipitor affects flexibility, there are potential side effects of the medication that could indirectly impact physical performance. If you are experiencing muscle pain, weakness, or inflammation while taking Lipitor, it's important to speak with your doctor to determine the best course of action.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463373/
[3] https://my.clevelandclinic.org/health/diseases/17604-vascular-disease