Based on the information available, there is no definitive evidence to suggest that Lipitor (atorvastatin), a medication used to treat high cholesterol, directly affects the effectiveness of medications used to treat Hepatitis C. However, it's important to note that both Lipitor and Hepatitis C medications are metabolized in the liver [1].

The liver is responsible for breaking down medications so they can be eliminated from the body. Therefore, any condition or medication that affects liver function could potentially impact the way other medications are metabolized.

The FDA label for Lipitor includes a warning about potential liver damage, but it does not specifically mention Hepatitis C [2]. Similarly, the label for Harvoni, a common Hepatitis C medication, does not list Lipitor as a drug that may interact with it [3].

However, it's always important for individuals to discuss any medications they are taking with their healthcare provider, especially if they have a liver condition or are taking medications that are metabolized in the liver. Healthcare providers can provide personalized advice based on a patient's individual health history and current medications [1].

In conclusion, while there is no direct evidence to suggest that Lipitor affects the effectiveness of Hepatitis C medications, both drugs are metabolized in the liver. Therefore, it's important for individuals taking both medications to discuss this with their healthcare provider.

Sources:
[1] DrugPatentWatch.com, "Lipitor (Atorvastatin) Drug Profile", <https://www.drugpatentwatch.com/drugs/lipitor>.
[2] FDA, "Lipitor (Atorvastatin Calcium) Tablets, for Oral Use", <https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020990s053,021168s015lbl.pdf>.
[3] FDA, "Harvoni (Ledipasvir, Sofosbuvir) Tablets, for Oral Use", <https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/206380s000lbl.pdf>.