Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. According to the National Health Service (NHS) [3], Lipitor should be taken once a day, with or without food. However, the Cleveland Clinic [2] recommends taking Lipitor at the same time every day, with or without food. The medication should be swallowed whole with a glass of water and not crushed or chewed.

As with any medication, Lipitor can have side effects. According to Drug Patent Watch [1], common side effects of Lipitor include headache, muscle pain, joint pain, diarrhea, and nausea. These side effects are usually mild and go away on their own. However, if they persist or become severe, it is recommended to consult a healthcare provider.

In rare cases, Lipitor can cause serious side effects such as liver problems, muscle damage, and an increased risk of diabetes. Patients should contact their healthcare provider immediately if they experience symptoms such as unexplained muscle pain, tenderness, or weakness, dark-colored urine, or yellowing of the skin or eyes.

In conclusion, Lipitor can be taken with or without food, but it is recommended to take it at the same time every day. Common side effects of Lipitor include headache, muscle pain, joint pain, diarrhea, and nausea. However, in rare cases, Lipitor can cause serious side effects such as liver problems, muscle damage, and an increased risk of diabetes. Patients should consult their healthcare provider if they experience any concerning symptoms.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://my.clevelandclinic.org/health/treatments/22282-statins
[3] https://www.nhs.uk/medicines/atorvastatin/how-and-when-to-take-atorvastatin/