Lipitor, also known as atorvastatin, is a medication that belongs to a class of drugs called statins. It is commonly prescribed to lower cholesterol levels in patients with high cholesterol and to reduce the risk of heart disease.

According to the Drug Patent Watch [1], Lipitor works by inhibiting an enzyme called HMG-CoA reductase, which is responsible for producing cholesterol in the liver. By inhibiting this enzyme, Lipitor reduces the amount of cholesterol that is produced, which in turn lowers the amount of cholesterol in the bloodstream.

The National Center for Biotechnology Information [2] states that statins, including Lipitor, have been shown to have a modest effect on reducing the absorption of dietary fat. However, the exact mechanism of this effect is not well understood. One theory is that statins may reduce the activity of enzymes that break down fat in the intestine, which could lead to a decrease in fat absorption.

A study published in the journal Clinical Pharmacology and Therapeutics [3] found that Lipitor did not significantly affect the absorption of dietary fat in healthy volunteers. However, the study did find that Lipitor increased the absorption of certain fat-soluble vitamins, including vitamin E and beta-carotene.

In conclusion, while statins like Lipitor may have a modest effect on reducing the absorption of dietary fat, the exact mechanism of this effect is not well understood. A study found that Lipitor did not significantly affect the absorption of dietary fat, but did increase the absorption of certain fat-soluble vitamins. It is important to talk to a healthcare provider about any concerns or questions regarding Lipitor or any other medication.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/books/NBK430779/
[3] https://pubmed.ncbi.nlm.nih.gov/8568017/