Aspirin and Lipitor are two different medications that are often prescribed for different purposes. Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, reduce fever, and prevent blood clots. Lipitor, on the other hand, is a statin drug that is used to lower cholesterol levels in the blood.

According to the sources provided, there is no direct evidence that suggests that aspirin worsens Lipitor side effects. However, both aspirin and Lipitor can cause gastrointestinal side effects, such as heartburn, indigestion, and stomach ulcers [2]. Therefore, taking both medications together may increase the risk of these side effects.

It is important to note that the combination of aspirin and Lipitor should only be taken under the guidance of a healthcare professional. Patients should inform their doctor if they experience any side effects while taking these medications. In addition, patients should follow the prescribed dosage and not exceed the recommended amount of either medication.

In conclusion, there is no direct evidence that suggests that aspirin worsens Lipitor side effects. However, taking both medications together may increase the risk of gastrointestinal side effects. Patients should consult their healthcare provider before taking both medications together and should report any side effects they experience.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ASPIRIN
[2] https://www.mayoclinic.org/diseases-conditions/gerd/expert-answers/heartburn-gerd/faq-20058535
[3] https://www.frontiersin.org/articles/10.3389/fphar.2021.589418/full