Lipitor is a medication used to treat high cholesterol levels. The dosage of Lipitor should be determined by a healthcare professional based on the patient's medical history, cholesterol levels, and other factors. The initial recommended dose of Lipitor is usually 10-20 mg per day, which can be increased to a maximum of 80 mg per day if necessary [3].

According to the drug patent watch website, Lipitor's dosage should be increased based on the patient's response to the medication. If the patient's cholesterol levels remain high after several weeks of treatment, the dosage may be increased [1]. However, it is important to note that increasing the dosage of Lipitor may increase the risk of side effects, such as muscle pain and liver damage [2]. Therefore, any increase in dosage should be closely monitored by a healthcare professional.

A study published in the National Center for Biotechnology Information suggests that the effectiveness of Lipitor may be influenced by genetic factors. The study found that patients with a certain genetic variation may require a higher dose of Lipitor to achieve the same cholesterol-lowering effect as patients without the variation [2]. Therefore, genetic testing may be necessary to determine the appropriate dosage for some patients.

In summary, the dosage of Lipitor should be determined by a healthcare professional based on the patient's medical history and cholesterol levels. If the patient's cholesterol levels remain high after several weeks of treatment, the dosage may be increased, but this should be closely monitored for potential side effects. Genetic testing may also be necessary to determine the appropriate dosage for some patients.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354082/
[3] https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/proper-use/drg-20067003