Advil is a brand name for ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation. Although Advil is generally safe and effective when used as directed, long-term use of the drug can increase the risk of several adverse effects.
One of the main risks of long-term Advil use is gastrointestinal (GI) complications, including bleeding, ulcers, and perforation of the stomach or intestines. According to the Australian Drug Foundation [2], NSAIDs such as Advil can irritate the lining of the stomach and cause inflammation, which can lead to the development of ulcers or bleeding. The risk of GI complications increases with age, duration of use, and higher doses of the drug.
Another potential risk of long-term Advil use is kidney damage. According to GoodRx [3], NSAIDs can reduce blood flow to the kidneys and impair their function, which can lead to kidney damage or failure. This risk is higher in people with pre-existing kidney disease, dehydration, or other medical conditions that affect the kidneys.
Long-term use of Advil can also increase the risk of cardiovascular events, such as heart attack or stroke. According to Drug Patent Watch [1], NSAIDs can increase blood pressure, cause fluid retention, and increase the risk of blood clots, all of which can contribute to cardiovascular complications. This risk is higher in people with pre-existing cardiovascular disease, high blood pressure, or other risk factors.
In conclusion, while Advil is generally safe and effective when used as directed, long-term use of the drug can increase the risk of several adverse effects, including gastrointestinal complications, kidney damage, and cardiovascular events. It is important to follow the recommended dosage and duration of use and to consult with a healthcare provider if you have any concerns about the use of Advil or other NSAIDs.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://adf.org.au/drug-facts/ibuprofen/
[3] https://www.goodrx.com/advil/advil-side-effects