Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. According to the National Health Service (NHS) [2], Lipitor can be taken with or without food. However, taking it with food may help reduce the risk of stomach upset. It is important to take Lipitor as directed by your doctor, usually once a day, at the same time each day. It is also important to continue taking Lipitor even if you feel well, as high cholesterol often has no symptoms but can still cause damage to your heart and blood vessels.

According to Drugs.com [3], taking Lipitor with food does not affect its effectiveness. However, it is recommended to avoid consuming grapefruit or grapefruit juice while taking Lipitor, as it can increase the levels of the medication in your bloodstream and increase the risk of side effects.

It is always important to follow your doctor's instructions regarding medication use, including how and when to take it, and whether to take it with or without food. If you have any questions or concerns about taking Lipitor, you should consult with your doctor or pharmacist.

Sources:
[2] https://www.nhs.uk/medicines/atorvastatin/how-and-when-to-take-atorvastatin/
[3] https://www.drugs.com/medical-answers/eat-food-taking-atorvastatin-3565628/
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR