Aspirin is a widely used medication for pain relief, fever reduction, and inflammation. It is a nonsteroidal anti-inflammatory drug (NSAID) that works by blocking the production of certain chemicals in the body that cause pain and inflammation [2]. However, like any medication, aspirin can interact with other drugs, which can lead to potentially harmful side effects.

According to the DrugPatentWatch database [1], aspirin has no known drug interactions with any other medications. However, this does not mean that aspirin is completely safe to take with any medication. The NHS Inform website [2] states that aspirin can interact with other NSAIDs, such as ibuprofen and naproxen, which can increase the risk of side effects such as stomach bleeding. Aspirin can also interact with blood-thinning medications such as warfarin, heparin, and clopidogrel, which can increase the risk of bleeding.

Drugs.com [3] provides a more comprehensive list of potential drug interactions with aspirin, which includes over 500 medications. Some of the most common drugs that can interact with aspirin include:

- Anticoagulants (blood thinners) such as warfarin, heparin, and clopidogrel
- Other NSAIDs such as ibuprofen and naproxen
- Steroids such as prednisone
- Antidepressants such as fluoxetine and sertraline
- Blood pressure medications such as lisinopril and enalapril
- Diabetes medications such as insulin and metformin
- Methotrexate, a medication used to treat cancer and autoimmune diseases

It is important to note that this is not a complete list, and there may be other medications that can interact with aspirin. Therefore, it is always important to talk to your doctor or pharmacist before taking aspirin with any other medication, including over-the-counter drugs and herbal supplements.

In conclusion, aspirin is generally safe to take with most medications, but it can interact with certain drugs, which can lead to potentially harmful side effects. It is important to talk to your doctor or pharmacist before taking aspirin with any other medication to avoid any potential drug interactions.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ASPIRIN
[2] https://www.nhsinform.scot/tests-and-treatments/medicines-and-medical-aids/types-of-medicine/aspirin
[3] https://www.drugs.com/drug-interactions/aspirin.html