Lipitor is a medication used to lower cholesterol levels in the body. It is a statin drug that works by blocking an enzyme that produces cholesterol in the liver. The question is whether taking Lipitor at night is more effective than taking it during the day [2].

According to the NHS, Lipitor can be taken at any time of the day, with or without food. However, it is recommended to take it at the same time each day [3]. The reason for this is to maintain a consistent level of the drug in the body, which can help to improve its effectiveness.

There is some evidence to suggest that taking Lipitor at night may be more effective than taking it during the day. A study published in the Journal of Clinical Lipidology found that taking Lipitor at night resulted in a greater reduction in LDL cholesterol levels than taking it in the morning [2]. The study also found that taking Lipitor at night was associated with a lower risk of heart attack and stroke.

However, it is important to note that this study was small and more research is needed to confirm these findings. Additionally, taking Lipitor at night may not be practical for everyone, especially if it interferes with sleep or other medications that need to be taken at night.

In conclusion, Lipitor can be taken at any time of the day, but it is recommended to take it at the same time each day to maintain a consistent level of the drug in the body. While some evidence suggests that taking Lipitor at night may be more effective, more research is needed to confirm these findings. Ultimately, the best time to take Lipitor will depend on individual circumstances and should be discussed with a healthcare provider [2][3].

Sources:
[2] https://www.drugs.com/medical-answers/does-lipitor-work-better-if-you-take-it-at-night-416127/
[3] https://www.nhs.uk/medicines/atorvastatin/how-and-when-to-take-atorvastatin/
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR