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Can advil and alcohol increase liver enzyme levels?



Advil is a brand name for ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to relieve pain and reduce inflammation. According to Drug Patent Watch [1], ibuprofen is metabolized in the liver by enzymes known as cytochrome P450s. Alcohol is also metabolized in the liver by the same enzymes, and consuming alcohol while taking ibuprofen can cause these enzymes to work harder, leading to an increase in liver enzyme levels. This increase in liver enzymes can be a sign of liver damage or inflammation, and it is important to monitor liver function if you are taking ibuprofen and drinking alcohol.

Toxic hepatitis is a condition in which the liver becomes inflamed due to exposure to toxins, including medications like ibuprofen and alcohol. According to a study published in the National Library of Medicine [2], ibuprofen can cause liver damage in some people, especially those who take high doses or have pre-existing liver disease. Alcohol can also cause liver damage, and the combination of alcohol and ibuprofen can increase the risk of liver damage.

The Mayo Clinic [3] states that symptoms of toxic hepatitis can include nausea, vomiting, abdominal pain, jaundice, and dark urine. If you experience any of these symptoms while taking ibuprofen and drinking alcohol, it is important to seek medical attention immediately. Your doctor may order liver function tests to monitor your liver enzymes and determine if there is any damage or inflammation.

In conclusion, taking Advil (ibuprofen) and drinking alcohol can increase liver enzyme levels, which can be a sign of liver damage or inflammation. It is important to monitor liver function if you are taking ibuprofen and drinking alcohol, and to seek medical attention if you experience any symptoms of toxic hepatitis.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921853/
[3] https://www.mayoclinic.org/diseases-conditions/toxic-hepatitis/symptoms-causes/syc-20352202



Follow-up:   How long does advil stay in the liver? Can advil cause liver damage alone? What are the symptoms of advil-induced liver damage?





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