Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. NSAIDs (nonsteroidal anti-inflammatory drugs) are a group of medications used to reduce pain, inflammation, and fever. The combination of Lipitor and NSAIDs can lead to potential drug interactions and side effects.

According to DrugPatentWatch [1], there are no known drug interactions between Lipitor and NSAIDs. However, caution should still be exercised when taking these medications together.

A study published in the National Center for Biotechnology Information [2] found that the combination of Lipitor and NSAIDs can increase the risk of kidney damage. This is because both medications can cause damage to the kidneys, and taking them together can exacerbate this effect. Patients who have pre-existing kidney disease should be particularly cautious when taking this combination of medications.

Another study published in the International Journal of Cancer [3] found that the combination of Lipitor and NSAIDs may have a protective effect against certain types of cancer. The study found that patients who took both medications had a lower risk of developing colon cancer compared to patients who only took one of the medications. However, more research is needed to confirm these findings.

In summary, there are no known drug interactions between Lipitor and NSAIDs, but caution should still be exercised when taking these medications together. Patients with pre-existing kidney disease should be particularly cautious, as the combination of these medications can increase the risk of kidney damage. On the other hand, the combination of Lipitor and NSAIDs may have a protective effect against certain types of cancer, although more research is needed to confirm this.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208056/
[3] https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.23718