Methotrexate is a medication used to treat various medical conditions such as cancer, autoimmune diseases, and psoriasis. Elderly patients who use methotrexate require special considerations.
According to Drug Patent Watch [1], Methotrexate is a generic drug that is available in various forms, including oral tablets, injectable solutions, and pre-filled syringes. The medication works by suppressing the immune system, which can lead to an increased risk of infections. Elderly patients who use methotrexate are at higher risk of developing infections due to their weakened immune systems.
The Centers for Disease Control and Prevention (CDC) [2] notes that immunocompromised individuals, including those who use methotrexate, are at higher risk of contracting infectious diseases while traveling. The CDC recommends that these individuals take extra precautions, such as getting vaccinated before traveling and avoiding contact with sick individuals.
A study published in the Journal of Geriatric Oncology [3] suggests that elderly patients who use methotrexate require close monitoring due to their increased risk of side effects, including gastrointestinal toxicity, liver toxicity, and bone marrow suppression. The study recommends that healthcare providers adjust the dosage of methotrexate and monitor elderly patients more frequently to prevent adverse reactions.
In conclusion, elderly patients who use methotrexate require special considerations due to their weakened immune systems, increased risk of infections, and higher risk of side effects. Healthcare providers should closely monitor these patients and adjust their dosage accordingly to prevent adverse reactions. Additionally, immunocompromised individuals who use methotrexate should take extra precautions while traveling to avoid contracting infectious diseases.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/METHOTREXATE
[2] https://wwwnc.cdc.gov/travel/yellowbook/2024/additional-considerations/immunocompromised-travelers
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153332/