Yes, there are affordable substitutes for Lipitor (atorvastatin), a medication used to treat high cholesterol and triglyceride levels. These alternatives include generic atorvastatin and other medications from different drug classes.

Generic atorvastatin is available in various strengths, and its price is typically lower than Lipitor's [1]. The cost difference is primarily due to the expiration of Lipitor's patent, allowing other manufacturers to produce and sell the generic version [1]. According to DrugPatentWatch.com, Lipitor's patent expired in November 2011 in the United States [2].

Additionally, other medications from different drug classes can be used to treat high cholesterol. These alternatives may have a more affordable cost or be covered better by insurance plans. Examples include bile acid sequestrants (e.g., colesevelam, cholestyramine), fibric acid derivatives (e.g., fenofibrate, gemfibrozil), and ezetimibe [3]. Consulting a healthcare professional is essential to determine the most appropriate and cost-effective treatment option.

Sources:

1. "Atorvastatin vs. Lipitor: What's the Difference?". Drugs.com. <https://www.drugs.com/atorvastatin-vs-lipitor.html>.
2. "Lipitor (Atorvastatin) Patent Expiration & Generics". DrugPatentWatch.com. <https://www.drugs.com/atorvastatin-vs-lipitor.html>.
3. "High Cholesterol Medications". Mayo Clinic. <https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/high-cholesterol-medications/art-20046098>.