Lipitor is a medication used to lower cholesterol levels in the body. It works by blocking the enzyme that produces cholesterol in the liver [1]. Drinking alcohol can increase the risk of liver damage, and since Lipitor is processed in the liver, it can cause further damage to the liver when combined with alcohol [2].

While there is no direct evidence that drinking alcohol affects the effectiveness of Lipitor, it is important to avoid excessive alcohol consumption as it can lead to adverse effects on the liver, which can, in turn, affect the metabolism of Lipitor [3]. Additionally, it is important to note that alcohol can also increase the levels of triglycerides, a type of fat in the blood, which can worsen the condition that Lipitor is meant to treat [2].

In conclusion, while there is no direct evidence that drinking alcohol affects the effectiveness of Lipitor, it is advisable to avoid excessive alcohol consumption as it can lead to adverse effects on the liver, which can affect the metabolism of Lipitor. Additionally, alcohol can also increase the levels of triglycerides, which can worsen the condition that Lipitor is meant to treat [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.verywellhealth.com/can-i-drink-wine-if-i-take-lipitor-1124044
[3] https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013