Lipitor is a brand name for the drug atorvastatin, which is used to lower cholesterol levels in the blood. According to the National Health Service (NHS) [2], it is safe to take most painkillers with atorvastatin, including paracetamol (also known as acetaminophen or Tylenol), aspirin, ibuprofen, and naproxen. However, the NHS advises that you should always check with a healthcare professional before taking any new medication, including over-the-counter painkillers, while taking atorvastatin.

Drugs.com [3] also confirms that paracetamol is safe to take with atorvastatin. However, it advises that you should avoid taking high doses of paracetamol (more than 4 grams per day) as this can increase the risk of liver damage. Additionally, Drugs.com notes that some other painkillers, such as nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and naproxen, can interact with atorvastatin and increase the risk of side effects such as muscle pain and kidney damage. Therefore, it is important to speak with a healthcare professional before taking these medications together.

Drugpatentwatch [1] provides information on the patent status of Lipitor but does not provide any information on the safety of taking painkillers with atorvastatin.

In summary, most painkillers, including paracetamol, are safe to take with atorvastatin (Lipitor) according to the NHS [2] and Drugs.com [3]. However, it is important to speak with a healthcare professional before taking any new medication, including over-the-counter painkillers, while taking atorvastatin. It is also important to avoid taking high doses of paracetamol and to be cautious when taking NSAIDs such as ibuprofen and naproxen.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.nhs.uk/medicines/atorvastatin/taking-atorvastatin-with-other-medicines-and-herbal-supplements/
[3] https://www.drugs.com/drug-interactions/atorvastatin-with-tylenol-276-0-11-12.html