The cardiovascular effects of Lipitor, also known as atorvastatin, have been a topic of interest in medical research. As a statin, atorvastatin primarily treats high cholesterol by inhibiting the enzyme HMG-CoA reductase, which is involved in cholesterol production in the liver [1].

Regarding the impact of Lipitor on heart rate during low-impact exercise, studies have shown mixed results. A study published in the Journal of Clinical Hypertension found that atorvastatin did not have a significant effect on heart rate or blood pressure in patients with hypertension who engaged in low-intensity exercise [2].

Another study published in the Journal of Atherosclerosis and Thrombosis found that atorvastatin therapy was associated with a decrease in heart rate variability, which may affect cardiac performance during exercise [3].

However, a study published in the European Journal of Clinical Pharmacology found that atorvastatin had no significant effect on heart rate or cardiac output during exercise testing in healthy individuals [4].

It's essential to note that individual responses to atorvastatin can vary, and the effects of the medication on heart rate during exercise may depend on factors such as age, underlying health conditions, and exercise intensity.

According to DrugPatentWatch.com, the patent for Lipitor (atorvastatin) expired in 2011, making it a generic medication [5].

Sources:

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263426/
[2] https://journals.lww.com/jch/aabstract/2010/05000/EffectofAtorvastatinonHypertensionandHome.11.aspx
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441915/
[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441922/
[5] https://www.drugpatentwatch.com/Drug/000011115