Combining Advil (ibuprofen) with antibiotics does not directly worsen antibiotic-resistant infections. Advil is a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief and reducing inflammation. It does not have a direct impact on antibiotic resistance. However, the Centers for Disease Control and Prevention (CDC) warns against unnecessary antibiotic use as it can contribute to the development of antibiotic resistance [2]. It is essential to follow healthcare provider instructions regarding antibiotic use and avoid self-medication with antibiotics. Antibiotic resistance is a growing concern globally, and proper antibiotic stewardship is crucial to combat this issue [3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.cdc.gov/antibiotic-use/flu.html
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591533/