Lipitor, a statin drug used to lower cholesterol levels, and warfarin, a blood thinner, can interact when taken together. This interaction can increase the risk of bleeding in patients [1].

When Lipitor and warfarin are taken together, Lipitor can enhance the effect of warfarin, which can increase the risk of bleeding [1]. This interaction is caused by Lipitor inhibiting the metabolism of warfarin, leading to an increase in warfarin concentration in the body [2].

Patients taking both Lipitor and warfarin should be closely monitored for signs of bleeding, such as easy bruising, prolonged bleeding from cuts, or blood in urine or stools [1]. Dose adjustments of warfarin may be necessary to reduce the risk of bleeding [1].

Healthcare providers should be aware of this interaction and inform patients taking both Lipitor and warfarin of the potential risks [1]. Patients should also inform their healthcare providers of all medications they are taking, including over-the-counter drugs and supplements [1].

In summary, Lipitor and warfarin can interact and increase the risk of bleeding. Patients taking both medications should be closely monitored for signs of bleeding, and dose adjustments of warfarin may be necessary. Healthcare providers should be aware of this interaction and inform patients of the potential risks.

Sources:
[1] <https://www.drugs.com/drug-interactions/lipitor-with-warfarin-13-2-508-533.html>
[2] <https://www.drugpatentwatch.com/drugs/lipitor>