After reviewing the available information, there is no definitive answer as to whether live vaccines should be deferred while on Cosentyx (secukinumab). However, it is generally recommended to avoid live vaccines during immunosuppressive therapy due to the risk of developing the infection that the vaccine is intended to prevent [1].

Cosentyx is a medication used to treat several conditions, including plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. It is a type of drug called a monoclonal antibody that works by targeting a specific protein in the body (interleukin-17A) to reduce inflammation [2].

According to the Cosentyx prescribing information, "the use of live vaccines should be avoided in patients treated with Cosentyx" [3]. However, the information does not provide specific details on the rationale behind this recommendation.

It is important to note that the decision to administer live vaccines while on Cosentyx should be made on a case-by-case basis and in consultation with a healthcare provider. The provider will consider various factors, including the patient's overall health, the specific vaccine, and the potential risks and benefits of vaccination [1].

In summary, while there is no definitive answer as to whether live vaccines should be deferred while on Cosentyx, it is generally recommended to avoid live vaccines during immunosuppressive therapy. Patients should consult with their healthcare provider to determine the best course of action.

Sources:

1. <https://www.cdc.gov/vaccines/covid-19/info-by-product/pfizer.html>
2. <https://www.drugs.com/cosentyx.html>
3. <https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/125557s000lbl.pdf>
4. <https://www.drugpatentwatch.com/drugs/cosentyx>