Based on the information available, there is no definitive evidence to suggest that Lipitor, a medication used to treat high cholesterol, directly affects the effectiveness of blood pressure drugs [1].

Lipitor, also known as atorvastatin, is a statin drug that works by reducing the amount of cholesterol produced by the body [1]. Blood pressure drugs, on the other hand, are used to treat high blood pressure and work in various ways, such as relaxing blood vessels or reducing the amount of fluid in the body [2].

While both Lipitor and blood pressure drugs are often used together to manage cardiovascular risk factors, they target different aspects of heart health [3]. Lipitor is primarily used to lower cholesterol levels, while blood pressure drugs are used to control high blood pressure.

It is important to note that while these medications do not directly interact with each other, they can both affect the kidneys, which are responsible for filtering waste and excess fluids from the body [4]. Therefore, it is crucial for individuals taking both Lipitor and blood pressure drugs to be monitored by a healthcare professional to ensure that their kidneys are functioning properly.

In summary, while Lipitor and blood pressure drugs do not directly affect each other's effectiveness, they can both impact kidney function, and it is essential for individuals taking both medications to be monitored by a healthcare professional.

Sources:
[1] "Atorvastatin." MedlinePlus, U.S. National Library of Medicine, 15 Feb. 2022, medlineplus.gov/druginfo/meds/a601245.html.
[2] "High Blood Pressure Medicines." MedlinePlus, U.S. National Library of Medicine, 15 Feb. 2022, medlineplus.gov/highbloodpressuremedicines.html.
[3] "Lipitor." Drugs.com, www.drugs.com/lipitor.html.
[4] "Statins." Mayo Clinic, Mayo Foundation for Medical Education and Research, 21 Jan. 2022, www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statins/art-20045786.