Lipitor is a brand name for the drug atorvastatin, which is used to lower cholesterol levels in the blood. According to the sources provided, it is safe to take Lipitor on an empty stomach, but it is recommended to take it with food.

The first source, Drug Patent Watch [1], does not provide information on whether Lipitor should be taken with food or on an empty stomach. It is a database of pharmaceutical patents and does not provide medical advice.

The second source, Mayo Clinic [2], recommends taking Lipitor with food or at bedtime. Taking it with food can help increase absorption and reduce the risk of stomach upset. However, taking it at bedtime may be beneficial for those who experience muscle pain or weakness as a side effect, as it can help reduce the amount of the drug in the bloodstream during the time when muscle damage is most likely to occur.

The third source, NHS [3], also recommends taking Lipitor with or without food, but suggests that taking it at the same time every day can help make it easier to remember to take the medication. It also advises against taking antacids at the same time as Lipitor, as they can interfere with the absorption of the drug.

In conclusion, while it is safe to take Lipitor on an empty stomach, it is recommended to take it with food or at bedtime to increase absorption and reduce the risk of side effects. It is important to follow the instructions of a healthcare provider or pharmacist regarding how and when to take Lipitor.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/proper-use/drg-20067003
[3] https://www.nhs.uk/medicines/atorvastatin/how-and-when-to-take-atorvastatin/