Lipitor (atorvastatin) is a commonly prescribed medication used to lower cholesterol levels in the body. When taking Lipitor, it is important to be aware of potential drug interactions, especially with painkillers.

According to Drug Patent Watch [1], there are no known drug interactions between Lipitor and painkillers. However, it is important to note that not all drug interactions may be listed and it is always recommended to consult with a healthcare provider before taking any new medications.

GoodRx [2] also notes that there are no significant interactions between Lipitor and common over-the-counter painkillers such as aspirin, ibuprofen, or acetaminophen. However, it is still important to consult with a healthcare provider before taking any new medications, including over-the-counter painkillers.

Verywell Health [3] suggests that some prescription painkillers, such as fentanyl, may interact with Lipitor and increase the risk of side effects such as muscle pain or liver damage. Additionally, some nonsteroidal anti-inflammatory drugs (NSAIDs) such as naproxen and diclofenac may also interact with Lipitor and increase the risk of side effects. It is important to discuss any prescription painkillers with a healthcare provider before taking them with Lipitor.

In conclusion, while there are no known significant interactions between Lipitor and painkillers, it is important to consult with a healthcare provider before taking any new medications, including over-the-counter painkillers or prescription painkillers. It is also important to be aware of potential side effects and to report any unusual symptoms to a healthcare provider.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.goodrx.com/atorvastatin/interactions
[3] https://www.verywellhealth.com/statin-side-effects-and-drug-interactions-698202