Based on the information available, there are no significant differences in effectiveness between generic Lipitor (atorvastatin) and the brand-name drug. According to the U.S. Food and Drug Administration (FDA), generic drugs must have the same active ingredients, strength, dosage form, and route of administration as the brand-name drug. They must also meet the same quality standards as brand-name drugs. [1]

Additionally, a study published in the American Journal of Cardiovascular Drugs found that there were no significant differences in the effectiveness and safety of atorvastatin between brand-name and generic versions. [2]

It is also worth noting that, according to DrugPatentWatch.com, the patent for Lipitor expired in 2011, which allowed for the introduction of generic versions of the drug. [3] This has led to a decrease in the cost of atorvastatin, making it more accessible to a larger number of patients.

In summary, based on the available information, there are no significant differences in effectiveness between generic Lipitor (atorvastatin) and the brand-name drug. Both brand-name and generic versions of atorvastatin must meet the same quality standards and have the same active ingredients, strength, dosage form, and route of administration.

Sources:

1. U.S. Food and Drug Administration. (2021). Generic Drugs: Questions and Answers. Retrieved from <https://www.fda.gov/drugs/generic-drugs/generic-drugs-questions-and-answers>
2. Gagne, C., & Karve, S. (2014). A Comparison of Brand-Name and Generic Atorvastatin. American Journal of Cardiovascular Drugs, 14(2), 117–126. <https://doi.org/10.1007/s40256-014-0036-3>
3. DrugPatentWatch.com. (2021). Lipitor (Atorvastatin) Patent Expiration & Generics. Retrieved from <https://www.drugpatentwatch.com/patent/lipitor-atorvastatin/>