Vascepa is a medication that contains the active ingredient icosapent ethyl, which is used to reduce triglyceride levels in the blood. Compared to other medications used to treat high triglyceride levels, Vascepa has some unique characteristics.

One of the main differences between Vascepa and other medications is that it is a purified form of eicosapentaenoic acid (EPA), which is a type of omega-3 fatty acid. Other medications, such as Lovaza, contain a combination of EPA and docosahexaenoic acid (DHA), which is another type of omega-3 fatty acid.

According to a comparison on drugs.com [2], Vascepa and Lovaza have similar efficacy in reducing triglyceride levels, but Vascepa has been shown to have fewer side effects. Specifically, Vascepa has been associated with a lower risk of gastrointestinal side effects, such as diarrhea and nausea, compared to Lovaza.

Another difference between Vascepa and Lovaza is that Vascepa has been approved by the FDA for use in patients with elevated triglyceride levels who are also taking statin therapy to manage their cholesterol levels [3]. Lovaza, on the other hand, is approved for use in patients with very high triglyceride levels who are not responding to lifestyle changes alone [3].

Overall, Vascepa appears to be a safe and effective option for reducing triglyceride levels in patients who are also taking statin therapy. Compared to Lovaza, Vascepa may have fewer side effects and a more targeted indication for use. However, as with any medication, it is important to discuss the risks and benefits with your healthcare provider to determine the best treatment option for your individual needs.

Sources:
[2] https://www.drugs.com/compare/vascepa
[3] https://www.singlecare.com/blog/vascepa-vs-lovaza/