Ibuprofen, sold under the brand name Advil, is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce fever. Alcohol is a depressant that affects the central nervous system and can have various effects on the body, including the liver, brain, and heart.

According to Drug Patent Watch [1], there is no known interaction between alcohol and ibuprofen. However, taking ibuprofen with alcohol can increase the risk of stomach bleeding and may cause liver damage.

Healthline [2] advises that it is generally safe to take ibuprofen and drink alcohol in moderation. However, excessive alcohol consumption can increase the risk of gastrointestinal bleeding and liver damage, especially when taken with ibuprofen. Additionally, alcohol can increase the risk of side effects associated with ibuprofen, such as dizziness and stomach upset.

Medical News Today [3] warns that taking ibuprofen and drinking alcohol can increase the risk of stomach bleeding and may cause liver damage. They recommend avoiding alcohol while taking ibuprofen, especially if you have a history of stomach ulcers or liver problems.

In conclusion, while there is no known interaction between alcohol and ibuprofen, it is generally recommended to avoid excessive alcohol consumption while taking ibuprofen due to the increased risk of stomach bleeding and liver damage. It is always best to consult with a healthcare provider before taking any medication, especially if you have a history of liver problems or stomach ulcers.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ALCOHOL
[2] https://www.healthline.com/health/pain-relief/ibuprofen-alcohol
[3] https://www.medicalnewstoday.com/articles/mixing-ibuprofen-and-alcohol