Yes, alcohol use during early pregnancy can harm fetal brain development. According to the Centers for Disease Control and Prevention (CDC), alcohol use during pregnancy can cause a range of disorders known as Fetal Alcohol Spectrum Disorders (FASDs) [2]. FASDs are a group of conditions that can occur in a person whose mother drank alcohol during pregnancy [2].

Fetal alcohol exposure can lead to various physical, behavioral, and learning problems [2]. These problems can include birth defects, intellectual disabilities, and problems with behavior and learning [2]. Fetal alcohol exposure can also cause brain damage and problems with central nervous system function [1][3].

The National Institute of Health's National Center for Biotechnology Information states that alcohol is a teratogen, a substance that can cause birth defects [3]. Alcohol can interfere with the normal development of the brain and other organs in the fetus, and the risk of harm increases with the amount of alcohol consumed and the timing of alcohol exposure during pregnancy [3].

In summary, alcohol use during early pregnancy can harm fetal brain development and lead to a range of disorders known as Fetal Alcohol Spectrum Disorders (FASDs). The risk of harm increases with the amount of alcohol consumed and the timing of alcohol exposure during pregnancy.

Sources:
[1] <https://www.drugpatentwatch.com/p/tradename/ALCOHOL>
[2] <https://www.cdc.gov/ncbddd/fasd/alcohol-use.html>
[3] <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826810/>