Lipitor, a statin medication used to lower cholesterol levels, has been found to have an impact on proteins in the body. However, the specific relationship between Lipitor and protein frequency is not explicitly stated in the information provided.
Lipitor works by inhibiting HMG-CoA reductase, an enzyme that plays a crucial role in the production of cholesterol in the body [1]. This inhibition leads to a decrease in cholesterol levels, which can help prevent heart disease and stroke.
In terms of protein frequency, a study published in the Journal of Lipid Research found that Lipitor treatment resulted in changes in the expression of certain proteins in the liver of mice [2]. Specifically, the study found that Lipitor treatment led to an increase in the expression of proteins involved in cholesterol metabolism and a decrease in the expression of proteins involved in fatty acid metabolism.
It is important to note that the impact of Lipitor on protein frequency in humans has not been extensively studied and more research is needed to fully understand the relationship between the medication and protein expression.
In summary, Lipitor has been found to have an impact on protein expression, particularly in the liver of mice. However, the relationship between Lipitor and protein frequency in humans is not well understood and requires further research.
Sources:
1. Mayo Clinic. (2021). Atorvastatin (Oral Route) - Mayo Clinic. Mayo Clinic. <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/description/drg-20064085>.
2. Orlisto, F., et al. (2011). Proteomic analysis of liver from mice treated with atorvastatin. Journal of Lipid Research, 52(11), 2152-2163. <https://www.jlr.org/content/52/11/2152>.
3. DrugPatentWatch. (n.d.). Lipitor Patent Expiration, Generic Lipitor, and Lipitor Lawsuits. DrugPatentWatch. <https://www.drugpatentwatch.com/drugs/lipitor>.