Advil is a brand name for ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation [1]. According to drugs.com, ibuprofen can be taken with or without food, but taking it with food or milk may help to reduce stomach upset [2]. However, Healthline suggests that taking ibuprofen on an empty stomach may increase the risk of stomach irritation and bleeding, especially if taken regularly or in high doses [3].

It is important to note that the safety of taking Advil on an empty stomach may depend on the individual's health condition, age, and other medications they are taking. People with a history of stomach ulcers, bleeding disorders, or kidney or liver disease should consult their healthcare provider before taking Advil [3]. Additionally, taking Advil along with other NSAIDs, aspirin, or blood-thinning medications may increase the risk of bleeding and should be avoided [2].

In conclusion, Advil (ibuprofen) can be taken on an empty stomach, but it may increase the risk of stomach irritation and bleeding, especially if taken regularly or in high doses. It is recommended to take Advil with food or milk to reduce the risk of stomach upset. However, individuals with certain health conditions or taking certain medications should consult their healthcare provider before taking Advil [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.drugs.com/medical-answers/you-ibuprofen-empty-stomach-3572019/
[3] https://www.healthline.com/health/ibuprofen-on-empty-stomach